Anastrozole
Anastrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by reducing the amount of estrogen in the body, thereby slowing or stopping the growth of certain breast cancers that require estrogen to grow. Anastrozole is typically administered as a once-daily oral tablet, making it a convenient option for long-term management of breast cancer. Its effectiveness in lowering estrogen levels has made it a preferred choice in hormone therapy. Patients taking Anastrozole are advised to adhere to prescribed dosages to maximize its therapeutic benefits. Regular monitoring of bone density may be recommended, as long-term use can affect bone health.Active substance:
AnastrozolePharmachologic effect:
Anastrozole is a non-steroidal aromatase inhibitor, which works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of some breast cancers that need estrogen to grow.Indications:
- Treatment of postmenopausal women with hormone receptor-positive early breast cancer
- First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer
- Treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy
Contraindications:
- Pregnancy
- Premenopausal women
- Severe hepatic impairment
- Known hypersensitivity to anastrozole or any of the excipients
Side effects:
In order of decreasing probability: Very common: Hot flashes, asthenia, arthritis, pain, arthralgia, stiffness, Common: Nausea, headache, bone pain, rash, osteoporosis, fractures, Uncommon: Vaginal bleeding, vomiting, diarrhea, liver enzyme elevations, Rare: Allergic reactions, including angioedema, anaphylaxis
Dosing and Administration:
The recommended dose of Anastrozole is one 1 mg tablet taken once a day. It can be taken with or without food.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Anastrozole
in Cyrillic : Анастрозол
SUBSTANCE
Anastrozole
DOSAGE FORM
tablets
