Clopidogrel
Clopidogrel is an antiplatelet medication used primarily to prevent blood clots in patients at risk of heart attacks and strokes. It works by inhibiting platelets in the blood from sticking together, thereby reducing the risk of clot formation. Often prescribed for individuals with a history of cardiovascular disease, it is effective in improving blood flow and reducing the likelihood of future cardiovascular events. Clopidogrel is typically administered in tablet form and is well-regarded for its ability to provide long-term protection against clot-related complications. It is an essential medication in the management of coronary artery disease and peripheral vascular disease. Suitable for patients who require ongoing antiplatelet therapy, Clopidogrel plays a crucial role in maintaining vascular health.Active substance:
ClopidogrelPharmachologic effect:
Clopidogrel is an antiplatelet agent that inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor, thereby inhibiting platelet aggregation. This action helps to prevent thrombus formation in the arteries.Indications:
- Prevention of atherothrombotic events in patients with myocardial infarction
- Prevention of atherothrombotic events in patients with ischemic stroke
- Prevention of atherothrombotic events in patients with established peripheral arterial disease
- Acute coronary syndrome
Contraindications:
- Hypersensitivity to clopidogrel or any component of the product
- Active pathological bleeding such as peptic ulcer or intracranial hemorrhage
- Severe liver impairment
Side effects:
In order of decreasing probability: Common: bleeding, bruising, Uncommon: gastrointestinal discomfort, diarrhea, Rare: thrombocytopenia, neutropenia, Very rare: severe allergic reactions, liver function abnormalities
Dosing and Administration:
The recommended dose of clopidogrel for adults is 75 mg once daily, with or without food. In acute coronary syndrome, an initial loading dose of 300 mg may be given, followed by 75 mg once daily.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Clopidogrel
in Cyrillic : Клопидогрел
SUBSTANCE
Clopidogrel
DOSAGE FORM
tablets
