Terbinafine

Terbinafine

Terbinafine tablets are a potent antifungal medication primarily used to treat a wide range of fungal infections, including those affecting the skin and nails. As a member of the allylamine class, Terbinafine works by inhibiting the growth of fungi, ensuring effective relief from persistent infections. It is particularly effective against dermatophytes and is commonly prescribed for conditions like athlete's foot, ringworm, and onychomycosis (nail fungus). Regular use as prescribed helps restore healthy skin and nails. Terbinafine is well-absorbed orally and provides comprehensive systemic treatment. Ideal for those seeking targeted antifungal therapy.

Active substance:

Terbinafine

Pharmachologic effect:

Terbinafine is an antifungal medication that works by inhibiting the enzyme squalene epoxidase, leading to a deficiency in ergosterol and an accumulation of squalene within the fungal cell, resulting in fungal cell death.

Indications:


  • Onychomycosis (fungal infection of the nail)
  • Tinea capitis (scalp ringworm)
  • Tinea corporis (ringworm of the body)
  • Tinea cruris (jock itch)
  • Tinea pedis (athlete's foot)

Contraindications:


  • Hypersensitivity to terbinafine or any of the excipients
  • Chronic or active liver disease
  • Severe renal impairment

Side effects:


In order of decreasing probability: Common: Headache, gastrointestinal disturbances (diarrhea, dyspepsia, nausea, abdominal pain), skin reactions (rash, urticaria), Uncommon: Taste disturbances, musculoskeletal pain (myalgia, arthralgia), Rare: Hepatic dysfunction, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), Very rare: Anaphylactic reactions, blood disorders (neutropenia, thrombocytopenia)

Dosing and Administration:


The recommended dose for adults is 250 mg once daily. The duration of treatment varies depending on the indication: 6 weeks for fingernail onychomycosis, 12 weeks for toenail onychomycosis, and 2 to 6 weeks for skin infections.

Storage:


Store at a temperature not exceeding 25°C (77°F).


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Terbinafine
in Cyrillic : Тербинафин
SUBSTANCE
Terbinafine
DOSAGE FORM
tablets

Out Of Stock


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