Celecoxib
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) primarily used to alleviate pain and inflammation in conditions such as arthritis. It works by reducing hormones that cause inflammation and pain in the body. Available in capsule form, Celecoxib offers a convenient way to manage symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. The medication is designed for those who require consistent pain management. Celecoxib's targeted action helps reduce joint stiffness and swelling, improving daily function and quality of life. It is recommended for individuals seeking effective relief from chronic inflammatory conditions.Active substance:
CelecoxibPharmachologic effect:
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2), leading to a decrease in the formation of prostaglandins, which are mediators of pain and inflammation.Indications:
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute pain management
- Primary dysmenorrhea
Contraindications:
- Hypersensitivity to celecoxib or any component of the formulation
- History of allergic-type reactions to sulfonamides
- History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs
- Severe hepatic impairment
- Severe renal impairment
- Coronary artery bypass graft (CABG) surgery
- Pregnancy, particularly in the third trimester
Side effects:
In order of decreasing probability: Common: Headache, hypertension, diarrhea, nausea, Uncommon: Dizziness, abdominal pain, dyspepsia, flatulence, Rare: Gastrointestinal bleeding, renal impairment, hypersensitivity reactions
Dosing and Administration:
For osteoarthritis, the recommended dose is 200 mg once daily or 100 mg twice daily. For rheumatoid arthritis, the recommended dose is 100 to 200 mg twice daily. For ankylosing spondylitis, the recommended dose is 200 mg once daily or 100 mg twice daily. For acute pain and primary dysmenorrhea, the initial dose is 400 mg, followed by an additional 200 mg if needed on the first day. On subsequent days, the recommended dose is 200 mg twice daily as needed.
Storage:
Store at a temperature not exceeding 30°C (86°F).
Celecoxib
in Cyrillic : Целекоксиб
SUBSTANCE
Celecoxib
DOSAGE FORM
capsules
