Clarithromycin
Clarithromycin is a macrolide antibiotic used to treat various bacterial infections. It is effective against a range of gram-positive and gram-negative bacteria. These tablets are commonly prescribed for respiratory tract infections, skin infections, and Helicobacter pylori eradication in peptic ulcer disease. The medication works by inhibiting protein synthesis in bacteria, thereby stopping their growth. It is available in tablet form, making it convenient for oral administration. Clarithromycin is often chosen for its broad spectrum of activity and its effectiveness in treating atypical pathogens. It is a reliable choice for patients needing a potent antibacterial agent.Active substance:
ClarithromycinPharmachologic effect:
Clarithromycin is a macrolide antibiotic that works by inhibiting bacterial protein synthesis, thereby stopping the growth of bacteria. It is effective against a wide variety of gram-positive and gram-negative bacteria.Indications:
- Treatment of respiratory tract infections such as pneumonia and bronchitis
- Skin and soft tissue infections
- Helicobacter pylori eradication to reduce the risk of duodenal ulcer recurrence
- Acute otitis media
- Sinusitis
Contraindications:
- Hypersensitivity to clarithromycin, other macrolide antibiotics, or any of the excipients
- History of QT prolongation or ventricular cardiac arrhythmia, including torsades de pointes
- Severe hepatic failure in combination with renal impairment
- Concomitant use with drugs that are substrates of CYP3A4 and known to prolong QT interval
Side effects:
In order of decreasing probability: Common: Nausea, diarrhea, abdominal pain, taste perversion, Uncommon: Headache, insomnia, dyspepsia, Rare: Hepatic dysfunction, Stevens-Johnson syndrome, toxic epidermal necrolysis, Very rare: Anaphylactic reaction, torsades de pointes
Dosing and Administration:
The usual adult dose is 250 mg to 500 mg every 12 hours for 7 to 14 days, depending on the type and severity of the infection. For Helicobacter pylori eradication, the recommended dose is 500 mg twice daily in combination with other medications as part of a combination therapy.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Clarithromycin
in Cyrillic : Кларитромицин
SUBSTANCE
Clarithromycin
DOSAGE FORM
tablets
