Itraconazole
Itraconazole is an antifungal medication available in capsule form, designed to treat a variety of fungal infections. It works by inhibiting the growth of fungi, effectively managing conditions such as aspergillosis and onychomycosis. The capsules should be taken orally, and absorption is enhanced when taken with food. Itraconazole is known for its broad-spectrum efficacy against dermatophytes, yeasts, and molds. It is widely used in both acute and chronic fungal infections, providing reliable results. The medication is commonly prescribed for patients with compromised immune systems. Always ensure to follow dosage instructions as prescribed by a healthcare professional.Active substance:
ItraconazolePharmachologic effect:
Itraconazole is an antifungal medication that works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting cell membrane formation and leading to fungal cell death.Indications:
- Treatment of systemic mycoses
- Onychomycosis caused by dermatophytes and/or yeasts
- Vulvovaginal candidiasis
- Pityriasis versicolor
- Dermatophytosis
- Oral and esophageal candidiasis
Contraindications:
- Hypersensitivity to itraconazole or any of the excipients
- Pregnancy and lactation
- Concomitant use with certain medications such as cisapride, pimozide, quinidine, dofetilide, and others that may lead to QT prolongation
- Patients with ventricular dysfunction or a history of congestive heart failure
Side effects:
In order of decreasing probability: Common: Nausea, abdominal pain, dyspepsia, diarrhea, Uncommon: Headache, dizziness, fatigue, Rare: Hepatotoxicity, severe allergic reactions, Stevens-Johnson syndrome, peripheral neuropathy
Dosing and Administration:
The recommended dose for adults is 200 mg once daily. In severe infections, the dose may be increased to 200 mg twice daily. The capsules should be taken immediately after a full meal to ensure maximum absorption. Duration of treatment depends on the fungal infection being treated.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Itraconazole
in Cyrillic : Итраконазол
SUBSTANCE
Itraconazole
DOSAGE FORM
capsules
