Allopurinol
Allopurinol tablets are primarily used to manage and prevent gout attacks by reducing uric acid levels in the blood. This medication works by inhibiting the enzyme xanthine oxidase, which is responsible for the production of uric acid. Suitable for patients with chronic gout, Allopurinol helps in preventing joint pain and inflammation associated with high uric acid levels. Regular use of Allopurinol can also prevent kidney stones that form as a result of excessive uric acid. It is important to maintain consistent use for effective results. Allopurinol is generally well-tolerated and can be taken with or without food.Active substance:
AllopurinolPharmachologic effect:
Allopurinol is a xanthine oxidase inhibitor that reduces the production of uric acid in the body. It is used to prevent gout attacks and to treat high levels of uric acid in the blood, which can occur due to certain types of chemotherapy or kidney stones.Indications:
- Chronic gout
- Hyperuricemia associated with cancer therapy
- Recurrent calcium oxalate kidney stones
- Uric acid nephropathy
Contraindications:
- Hypersensitivity to allopurinol
- Acute gout attack
- Severe renal impairment
- Pregnancy and lactation
Side effects:
In order of decreasing probability: Rash, Nausea, Diarrhea, Drowsiness, Headache, Dizziness, Hypersensitivity reactions
Dosing and Administration:
The recommended starting dose is 100 mg per day, which may be increased by 100 mg weekly until the desired uric acid level is achieved. The maintenance dose typically ranges from 200 mg to 300 mg per day for mild conditions, and up to 600 mg to 800 mg per day for severe conditions. It should be taken after meals with plenty of fluids.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Allopurinol
in Cyrillic : Аллопуринол
SUBSTANCE
Allopurinol
DOSAGE FORM
tablets
