Captopril

Captopril

Captopril is an oral tablet used primarily to treat high blood pressure, also known as hypertension. It belongs to a class of medications called ACE inhibitors, which work by relaxing blood vessels, thereby lowering blood pressure and improving blood flow. Captopril is also used in the management of heart failure and may help prevent strokes, heart attacks, and kidney problems. It is crucial for patients who have experienced a heart attack or have diabetic kidney disease. Regular monitoring of kidney function and potassium levels is recommended during treatment. This medication is typically taken one to three times daily, with or without food.

Active substance:

Captopril

Pharmachologic effect:

Captopril is an angiotensin-converting enzyme (ACE) inhibitor that lowers blood pressure by relaxing blood vessels, improving blood flow, and reducing the workload on the heart.

Indications:


  • Hypertension
  • Heart failure
  • Left ventricular dysfunction after myocardial infarction
  • Diabetic nephropathy in type 1 diabetes

Contraindications:


  • Hypersensitivity to captopril or other ACE inhibitors
  • History of angioedema related to previous ACE inhibitor treatment
  • Hereditary or idiopathic angioedema
  • Pregnancy
  • Severe renal impairment

Side effects:


In order of decreasing probability: Cough, Dizziness, Rash, Taste disturbances, Hypotension, Hyperkalemia, Angioedema, Neutropenia, Renal impairment

Dosing and Administration:


The initial dose for hypertension is typically 12.5 mg to 25 mg two to three times daily. The dose may be adjusted based on patient response, with a usual maintenance dose of 25 mg to 50 mg two to three times daily. For heart failure, the initial dose is 6.25 mg to 12.5 mg three times daily, with a maintenance dose of 25 mg to 50 mg three times daily. Dosage may vary based on individual patient needs and should be adjusted by a healthcare professional.

Storage:


Store at a temperature not exceeding 25°C (77°F).


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Captopril
in Cyrillic : Каптоприл
SUBSTANCE
Captopril
DOSAGE FORM
tablets
MANUFACTURER

Out Of Stock


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