Clopidogrel
Clopidogrel is a medication primarily used to prevent blood clots in patients with cardiovascular conditions. It is an antiplatelet drug that works by inhibiting platelets in the blood from clumping together, thereby reducing the risk of heart attack and stroke. Clopidogrel is often prescribed for individuals who have recently experienced a heart attack, stroke, or have been diagnosed with peripheral artery disease. The medication is available in tablet form and should be taken as directed by a healthcare provider. Regular use of Clopidogrel can significantly improve cardiovascular outcomes and enhance patient quality of life. It is crucial for individuals on Clopidogrel to adhere to their prescribed regimen to ensure optimal effectiveness.Active substance:
ClopidogrelPharmachologic effect:
Clopidogrel is an antiplatelet medication that inhibits platelet aggregation by selectively and irreversibly binding to the adenosine diphosphate (ADP) receptor on platelets, thereby preventing the activation of the GPIIb/IIIa receptor complex. This action reduces the risk of thrombotic events such as heart attacks and strokes.Indications:
- Prevention of atherothrombotic events in patients with myocardial infarction, ischemic stroke, or established peripheral arterial disease
- Acute coronary syndrome
- Prevention of thrombotic events in patients with atrial fibrillation
Contraindications:
- Hypersensitivity to clopidogrel or any component of the product
- Active pathological bleeding such as peptic ulcer or intracranial hemorrhage
- Severe hepatic impairment
Side effects:
In order of decreasing probability: Common: bleeding, bruising, Uncommon: diarrhea, abdominal pain, dyspepsia, Rare: thrombocytopenia, neutropenia, aplastic anemia, Very rare: severe allergic reactions, including anaphylaxis
Dosing and Administration:
The recommended dose of clopidogrel for adults is 75 mg once daily, with or without food. In acute coronary syndrome, an initial loading dose of 300 mg may be given, followed by 75 mg once daily.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Clopidogrel
in Cyrillic : Клопидогрел
SUBSTANCE
Clopidogrel
DOSAGE FORM
tablets
