Spironolactone
Spironolactone is a potassium-sparing diuretic primarily used to treat hypertension and edema associated with heart failure, liver cirrhosis, or nephrotic syndrome. It works by blocking aldosterone, a hormone that causes water and sodium retention, thus helping reduce fluid buildup and lower blood pressure. Available in tablet form, Spironolactone provides an effective solution for individuals requiring long-term management of fluid retention. It is also used in cases of certain hormonal imbalances, such as hyperaldosteronism. The medication helps maintain potassium levels in the body, which is crucial for heart and muscle function. For optimal results, follow the prescribed dosage and maintain a consistent intake schedule.Active substance:
SpironolactonePharmachologic effect:
Spironolactone is a potassium-sparing diuretic that prevents the body from absorbing too much salt and keeps potassium levels from getting too low. It works by blocking the actions of the hormone aldosterone in the body, which can help reduce fluid retention and lower blood pressure.Indications:
- Edema associated with congestive heart failure
- Cirrhosis of the liver with ascites and edema
- Nephrotic syndrome
- Essential hypertension
- Hypokalemia
- Primary hyperaldosteronism
Contraindications:
- Anuria
- Acute renal insufficiency
- Significant impairment of renal excretory function
- Hyperkalemia
- Addison's disease
- Hypersensitivity to spironolactone or any component of the formulation
Side effects:
In order of decreasing probability: Hyperkalemia, Hyponatremia, Dizziness, Headache, Gastrointestinal disturbances, Rash, Gynecomastia, Menstrual irregularities, Impotence
Dosing and Administration:
The recommended initial dose for adults is 25 to 100 mg daily, administered in single or divided doses. Dosage may be adjusted based on patient response and clinical condition. For specific conditions such as primary hyperaldosteronism, dosing may vary and should be determined by a healthcare professional.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Spironolactone
in Cyrillic : Спиронолактон
SUBSTANCE
Spironolactone
DOSAGE FORM
tablets
