Selank®

Selank®

Selank is a sedative drug that acts in several ways:

  • Anxiolytic : Selank affects the primary link of anxiety - it prevents an increase in the level of norepinephrine and serotonin in the emotional zones of the brain, and a decrease in the concentration of enkephalins
  • Anti-depressive : Selank normalizes the level of enkephalins and serotonin in emotional zones. Selank stimulates the synthesis of serotonin when it is low, and when the level of monoamine is high, it blocks it.
  • Stress- protective : Selank eliminates emotional and negative tension, restores motivational activity and activates adaptive behavior aimed at achieving a useful result.
  • Nootropic : Selank has a positive effect on the mnestic and cognitive functions of the human brain. Selank activates the processes of learning, memory, analysis and reproduction of information.

Why drops?

The intranasal route of administration of drugs that improve brain function is more effective than others, because drugs, when instilled into the nose along the olfactory nerves, can be transported directly to the brain tissue.
The form of administration in the form of nasal drops provides a high speed of onset of action (from 5 minutes), a bioavailability of 92.8%, the absence of drug interactions, compatibility with alcohol and a number of other advantages.
The intranasal route of administration gives Selank huge advantages over drug preparations in the form of injections or tablets - after all, their effectiveness is significantly limited by the protective barriers of the body, for example, the blood-brain barrier, whose task is to prevent aggressive compounds from reaching the brain cells.
And drugs for the body are a kind of "aggressors" and most of them do not reach the brain, and if they penetrate the brain, then only in small quantities.
It is also worth considering that intranasal administration does not cause any inconvenience to the patient and does not require special procedures that require qualified personnel.
Just a few minutes after Selank hits the nasal mucosa, it begins to act by helping brain cells. It is very important for each person to quickly recover and return to their usual activities, which Selank helps.



Active substance:

synthetic Tuftsin ( threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline-diacetate )

Pharmachologic effect:

anxiolytic, antidepressant, nootropic, antiasthenic

Pharmacodynamics:


Selank is a synthesized analogue of the endogenous peptide tuftsin, which has an original mechanism of neurospecific action on the central nervous system.
Selank has an anti-anxiety effect with an antidepressant effect; anti-asthenic action.
Selank relieves symptoms of anxiety, anxiety, fear, apathy, depression and asthenia.
It has a positive effect on cognitive functions, improves memory, speech, increases attention, activates learning processes, in particular, memorization, analysis and reproduction of information. Normalizes psychomotor reactions.
Under stress, Selank eliminates emotional and negative tension and stimulates the development of adaptive behavior aimed at achieving a useful result.

Pharmacokinetics:


Selank is administered intranasally (nasal drops). The absolute bioavailability of Selank when administered to the nasal mucosa is 92.8%. The drug is rapidly absorbed from the nasal mucosa and after 30 seconds is found in the blood plasma, and then quickly distributed to various organs and tissues. Penetrates into brain tissue. Plasma concentration progressively decreases over 5-5.5 minutes. In daily urine, neither unchanged drug nor metabolites are detected, which is due to the rapid degradation of Selank under the influence of tissue peptidases.

Indications:


unmotivated anxiety, anxiety;
panic attacks;
neurasthenia;
asthenia;
instability of mood;
sleep disorders;
decreased will, initiation of activity, indecision, difficulty in making decisions, self-doubt;
insecurity in communication;
adjustment disorders;
Prevention and treatment of stress disorders.

Contraindications:


Individual intolerance to the drug.
Pregnancy, breastfeeding period (efficacy and safety studies have not been conducted).
Children under 18 years of age (efficacy and safety studies have not been conducted).

Side effects:


With increased sensitivity to the perception of smell and taste, when the drug gets from the nasal cavity to the mucous membrane of the pharynx, unpleasant taste sensations may appear. Perhaps the development of allergic reactions with individual intolerance.


Interaction:


Selankdoes not affect the effects of drugs that depress and stimulate the central nervous system - haloperidol, pentobarbital, hexobarbital, analeptics.
Selank can be combined with any psycho- and neuroactive therapy.
Selank is safe when combined with ethanol-containing products.

Dosing and Administration:


Selank is administered intranasally.
Remove the plastic screw cap from the vial for initial use and replace it with the capped pipette provided.
Take the drug into a pipette.
Squeeze the required number of drops of the drug onto the clean mucous membrane of the nasal passage, then pinch the nostril with your finger for a short time.
Instillation of the drug into the nasal passages is carried out in a sitting position with the head slightly thrown back or tilted to one side, after which each nostril is clamped with a finger for a short time.
Absorption efficiency may decrease in the presence of increased secretions from the nasal mucosa, so it is recommended to clear the nasal passage before use (instillation).
Dose: 2 drops in each nasal passage 3 times a day.
The duration of the course of the drug is 14 days. If necessary, the course of treatment can be repeated after 1-3 weeks, after consulting a doctor.
Use the drug only according to the method of application and in the doses indicated in the instructions. If necessary, please consult your doctor before taking the medicine.

Overdose:


Cases of overdose are not registered.

Special instructions:
Selank does not cause the phenomena of drug dependence and addiction.

Storage:


In long term store in a place protected from light, at a temperature not exceeding 10°C (50°F ).
Do not freeze. Store the opened vial at a temperature not exceeding 25°C (77°F ) for no more than 15 days.


Write a review

Please login to review
Selank®
in Cyrillic : Селанк
SUBSTANCE
Tuftsin (synthesized)
DOSAGE FORM
nasal drops
MANUFACTURER

In Stock

available pack options :

0.15% 3ml nasal drops $20.60
price shown for :

1 reviews /
Write a review