Loperamide-Akrihin

Active substance:

Loperamide Hydrochloride

Pharmachologic effect:

Loperamide is an anti-diarrheal medication that works by slowing down the movement of the gut. This decreases the number of bowel movements and makes the stool less watery.

Indications:

• Acute diarrhea
• Chronic diarrhea associated with inflammatory bowel disease
• Reduction of the volume of discharge in patients with ileostomies

Contraindications:

• Hypersensitivity to loperamide or any of the excipients
• Abdominal pain without diarrhea
• Acute dysentery characterized by blood in stools and high fever
• Acute ulcerative colitis
• Bacterial enterocolitis caused by invasive organisms including Salmonella, Shigella, and Campylobacter
• Pseudomembranous colitis associated with the use of broad-spectrum antibiotics
• Children under 2 years of age

Side effects:

In order of decreasing probability: Common: Constipation, nausea, headache, Uncommon: Dizziness, flatulence, dry mouth, Rare: Abdominal pain, vomiting, hypersensitivity reactions

Dosing and Administration:

For adults, the initial dose is 4 mg (2 capsules), followed by 2 mg (1 capsule) after each loose stool. The maximum daily dose should not exceed 16 mg (8 capsules). For children aged 6-12 years, the dosage should be adjusted according to body weight and under medical supervision.

Storage:

Store at a temperature not exceeding 25°C (77°F).

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