Terbinafine

Terbinafine

Terbinafine is an oral antifungal medication primarily used to treat fungal infections affecting the skin, hair, and nails. It works by inhibiting the growth of fungi, providing relief from conditions such as athlete's foot, ringworm, and jock itch. The tablets are known for their effectiveness in eliminating fungal infections by targeting the underlying cause. Terbinafine is available in tablet form, offering a convenient option for those who prefer oral treatment over topical applications. It’s particularly effective against dermatophytes, a type of fungus that causes skin diseases. The treatment duration can vary depending on the severity and location of the infection, but the medication is generally considered fast-acting. Its oral administration ensures comprehensive treatment, reaching deep-seated infections that topical solutions might miss.

Active substance:

Terbinafine

Pharmachologic effect:

Terbinafine is an antifungal medication that works by inhibiting the enzyme squalene epoxidase, leading to a deficiency in ergosterol and an accumulation of squalene within the fungal cell. This results in fungal cell death, effectively treating infections caused by dermatophytes and certain yeasts.

Indications:


  • Onychomycosis (fungal infections of the nail)
  • Tinea pedis (athlete's foot)
  • Tinea cruris (jock itch)
  • Tinea corporis (ringworm)
  • Tinea capitis (scalp ringworm)

Contraindications:


  • Hypersensitivity to terbinafine or any of the excipients
  • Chronic or active liver disease
  • Severe renal impairment

Side effects:


In order of decreasing probability: Common: Headache, gastrointestinal disturbances (diarrhea, dyspepsia, nausea, abdominal pain), Uncommon: Taste disturbances, rash, musculoskeletal pain, Rare: Hepatic dysfunction, severe skin reactions, blood disorders, Very rare: Anaphylactic reactions, severe liver failure

Dosing and Administration:


The recommended dose for adults is 250 mg once daily. The duration of treatment varies depending on the indication: for skin infections, treatment typically lasts 2 to 6 weeks; for onychomycosis, treatment may last 6 to 12 weeks. It is important to complete the full course of therapy as prescribed.

Storage:


Store at a temperature not exceeding 25°C (77°F).


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Terbinafine
in Cyrillic : Тербинафин
SUBSTANCE
Terbinafine
DOSAGE FORM
tablets
MANUFACTURER

In Stock

available pack options :

250mg x 14 tablets $15.70


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