Trental
Trental, containing the active ingredient Pentoxifylline, is primarily used to improve blood flow in patients with circulation problems. It works by decreasing the thickness of blood, allowing it to flow more easily through narrowed vessels, thus enhancing oxygen delivery throughout the body. This medication is commonly prescribed for conditions such as peripheral artery disease and intermittent claudication, which can cause pain during walking. Trental tablets are an effective choice for managing symptoms related to poor circulation. Consistent use can lead to improved physical performance for patients. It is generally taken orally, with or without food, based on the physician's instructions. Trental's formulation is designed to maximize absorption and effectiveness.Active substance:
PentoxifyllinePharmachologic effect:
Trental improves blood flow by decreasing its viscosity, enhancing microcirculation, and increasing tissue oxygenation. It acts as a vasodilator and helps in improving peripheral blood circulation.Indications:
- Peripheral arterial occlusive disease
- Intermittent claudication
- Chronic cerebrovascular insufficiency
- Diabetic angiopathy
- Trophic disorders (e.g., leg ulcers, gangrene)
Contraindications:
- Hypersensitivity to pentoxifylline or other methylxanthines
- Recent cerebral hemorrhage
- Extensive retinal hemorrhages
- Acute myocardial infarction
- Severe coronary artery disease
- Severe arrhythmias
- Peptic ulcer disease
- Pregnancy and lactation
Side effects:
In order of decreasing probability: Nausea, Vomiting, Dizziness, Headache, Flushing, Hypotension, Tachycardia, Abdominal discomfort, Allergic reactions (e.g., rash, itching)
Dosing and Administration:
The recommended starting dose is 400 mg taken orally 2-3 times a day with meals. The dose may be adjusted based on patient response and tolerance. Maximum daily dose should not exceed 1200 mg.
Storage:
Store at a temperature not exceeding 25°C (77°F).
Trental
in Cyrillic : Трентал
SUBSTANCE
Pentoxifylline
DOSAGE FORM
tablets